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Magnetic Resonance Angiography MRAMRI Resource Directory:
 - MRA -
 
(MRA) Magnetic resonance angiography is a medical imaging technique to visualize blood filled structures, including arteries, veins and the heart chambers. This MRI technique creates soft tissue contrast between blood vessels and surrounding tissues primarily created by flow, rather than displaying the vessel lumen. There are bright blood and black blood MRA techniques, named according to the appearance of the blood vessels. With this different MRA techniques both, the blood flow and the condition of the blood vessel walls can be seen. Flow effects in MRI can produce a range of artifacts. MRA takes advantage of these artifacts to create predictable image contrast due to the nature of flow.
Technical parameters of the MRA sequence greatly affect the sensitivity of the images to flow with different velocities or directions, turbulent flow and vessel size.
This are the three main types of MRA:
All angiographic techniques differentially enhance vascular MR signal. The names of the bright blood techniques TOF and PCA reflect the physical properties of flowing blood that were exploited to make the vessels appear bright. Contrast enhanced magnetic resonance angiography creates the angiographic effect by using an intravenously administered MR contrast agent to selectively shorten the T1 of blood and thereby cause the vessels to appear bright on T1 weighted images.
MRA images optimally display areas of constant blood flow-velocity, but there are many situations where the flow within a voxel has non-uniform speed or direction. In a diseased vessel these patterns are even more complex. Similar loss of streamline flow occurs at all vessel junctions and stenoses, and in regions of mural thrombosis. It results in a loss of signal, due to the loss of phase coherence between spins in the voxel.
This signal loss, usually only noticeable distal to a stenosis, used to be an obvious characteristic of MRA images. It is minimized by using small voxels and the shortest possible TE. Signal loss from disorganized flow is most noticeable in TOF imaging but also affects the PCA images.
Indications to perform a magnetic resonance angiography (MRA):
•
Detection of aneurysms and dissections
•
Evaluation of the vessel anatomy, including variants
•
Blockage by a blood clot or stenosis of the blood vessel caused by plaques (the buildup of fat and calcium deposits)

Conventional angiography or computerized tomography angiography (CT angiography) may be needed after MRA if a problem (such as an aneurysm) is present or if surgery is being considered.

See also Magnetic Resonance Imaging MRI.
 
Images, Movies, Sliders:
 CE-MRA of the Carotid Arteries Colored MIP  Open this link in a new window
    
SlidersSliders Overview

 CE MRA of the Aorta  Open this link in a new window
    
SlidersSliders Overview

 TOF-MRA Circle of Willis Inverted MIP  Open this link in a new window
    

 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
SlidersSliders Overview

 
Radiology-tip.comradCT Angiography,  Angiogram
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Medical-Ultrasound-Imaging.comVascular Ultrasound,  Intravascular Ultrasound
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• Related Searches:
    • Coronary Angiography
    • Blood Pool Agents
    • Angiography
    • Partial Echo
    • Time of Flight Angiography
 
Further Reading:
  Basics:
Magnetic resonance angiography: current status and future directions
Wednesday, 9 March 2011   by www.jcmr-online.com    
MR–ANGIOGRAPHY(.pdf)
  News & More:
3-D-printed model of stenotic intracranial artery enables vessel-wall MRI standardization
Friday, 14 April 2017   by www.eurekalert.org    
Conventional MRI and MR Angiography of Stroke
2012   by www.mc.vanderbilt.edu    
MR Angiography Highly Accurate In Detecting Blocked Arteries
Thursday, 1 February 2007   by www.sciencedaily.com    
MRI Resources 
Lung Imaging - Raman Spectroscopy - Service and Support - Absorption and Emission - Case Studies - Sequences
 
Partial Fourier Technique
 
The partial Fourier technique is a modification of the Fourier transformation imaging method used in MRI in which the symmetry of the raw data in k-space is used to reduce the data acquisition time by acquiring only a part of k-space data.
The symmetry in k-space is a basic property of Fourier transformation and is called Hermitian symmetry. Thus, for the case of a real valued function g, the data on one half of k-space can be used to generate the data on the other half.
Utilization of this symmetry to reduce the acquisition time depends on whether the MRI problem obeys the assumption made above, i.e. that the function being characterized is real.
The function imaged in MRI is the distribution of transverse magnetization Mxy, which is a vector quantity having a magnitude, and a direction in the transverse plane. A convenient mathematical notation is to use a complex number to denote a vector quantity such as the transverse magnetization, by assigning the x'-component of the magnetization to the real part of the number and the y'-component to the imaginary part. (Sometimes, this mathematical convenience is stretched somewhat, and the magnetization is described as having a real component and an imaginary component. Physically, the x' and y' components of Mxy are equally 'real' in the tangible sense.)
Thus, from the known symmetry properties for the Fourier transformation of a real valued function, if the transverse magnetization is entirely in the x'-component (i.e. the y'-component is zero), then an image can be formed from the data for only half of k-space (ignoring the effects of the imaging gradients, e.g. the readout- and phase encoding gradients).
The conditions under which Hermitian symmetry holds and the corrections that must be applied when the assumption is not strictly obeyed must be considered.
There are a variety of factors that can change the phase of the transverse magnetization:
Off resonance (e.g. chemical shift and magnetic field inhomogeneity cause local phase shifts in gradient echo pulse sequences. This is less of a problem in spin echo pulse sequences.
Flow and motion in the presence of gradients also cause phase shifts.
Effects of the radio frequency RF pulses can also cause phase shifts in the image, especially when different coils are used to transmit and receive.
Only, if one can assume that the phase shifts are slowly varying across the object (i.e. not completely independent in each pixel) significant benefits can still be obtained. To avoid problems due to slowly varying phase shifts in the object, more than one half of k-space must be covered. Thus, both sides of k-space are measured in a low spatial frequency range while at higher frequencies they are measured only on one side. The fully sampled low frequency portion is used to characterize (and correct for) the slowly varying phase shifts.
Several reconstruction algorithms are available to achieve this. The size of the fully sampled region is dependent on the spatial frequency content of the phase shifts. The partial Fourier method can be employed to reduce the number of phase encoding values used and therefore to reduce the scan time. This method is sometimes called half-NEX, 3/4-NEX imaging, etc. (NEX/NSA). The scan time reduction comes at the expense of signal to noise ratio (SNR).
Partial k-space coverage is also useable in the readout direction. To accomplish this, the dephasing gradient in the readout direction is reduced, and the duration of the readout gradient and the data acquisition window are shortened.
This is often used in gradient echo imaging to reduce the echo time (TE). The benefit is at the expense in SNR, although this may be partly offset by the reduced echo time. Partial Fourier imaging should not be used when phase information is eligible, as in phase contrast angiography.

See also acronyms for 'partial Fourier techniques' from different manufacturers.
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• View the DATABASE results for 'Partial Fourier Technique' (6).Open this link in a new window

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Phase Contrast SequenceMRI Resource Directory:
 - Sequences -
 
(PC) Phase contrast sequences are the basis of MRA techniques utilizing the change in the phase shifts of the flowing protons in the region of interest to create an image. Spins that are moving along the direction of a magnetic field gradient receive a phase shift proportional to their velocity.
In a phase contrast sequence two data sets with a different amount of flow sensitivity are acquired. This is usually accomplished by applying gradient pairs, which sequentially dephase and then rephase spins during the sequence. Both 2D and 3D acquisition techniques can be applied with phase contrast MRA.
The first data set is acquired with a flow compensated sequence, i. e. without flow sensitivity. The second data set is acquired with a flow sensitive sequence. The amount of flow sensitivity is controlled by the strength of the bipolar gradient pulse pair, which is incorporated into the sequence. Stationary tissue undergoes no effective phase change after the application of the two gradients. Caused by the different spatial localization of flowing blood to stationary tissue, it experiences a different size of the second bipolar gradient compared to the first. The result is a phase shift.
The raw data from the two data sets are subtracted. By comparing the phase of signals from each location in the two sequences the exact amount of motion induced phase change can be determined to have a map where pixel brightness is proportional to spatial velocity.
Phase contrast images represent the signal intensity of the velocity of spins at each point within the field of view. Regions that are stationary remain black while moving regions are represented as grey to white.
The phase shift is proportional to the spin's velocity, and this allows the quantitative assessment of flow velocities. The difference MRI signal has a maximum value for opposite directions. This velocity is typically referred to as venc, and depends on the pulse amplitude and distance between the gradient pulse pair. For velocities larger than venc the difference signal is decreased constantly until it gets zero. Therefore, in a phase contrast angiography it is important to correctly set the venc of the sequence to the maximum flow velocity which is expected during the measurement. High venc factors of the PC angiogram (more than 40 cm/sec) will selectively image the arteries (PCA - arteriography), whereas a venc factor of 20 cm/sec will perform the veins and sinuses (PCV or MRV - venography).

See also Flow Quantification, Contrast Enhanced MR Venography, Time of Flight Angiography, Time Resolved Imaging of Contrast Kinetics.
 
Images, Movies, Sliders:
 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 
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• View the DATABASE results for 'Phase Contrast Sequence' (5).Open this link in a new window

 
Further Reading:
  Basics:
MR–ANGIOGRAPHY(.pdf)
MRI Resources 
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Velocity Encoding
 
(VENC) A specialized technique used for encoding flow-velocities.
The velocity encoding value is given by:
VENC = pi / gamma DELTA M1.
Gamma is the gyromagnetic ratio, and DELTA M1 is the gradient moment and is proportional to the area of the flow encoding gradient waveform.

See also Phase Contrast Sequence, Phase Contrast Angiography, and Bipolar Gradient Pulse.
 
Images, Movies, Sliders:
 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 
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• View the DATABASE results for 'Velocity Encoding' (2).Open this link in a new window

 
Further Reading:
  Basics:
Non-invasively Measuring Blood Flow Using Magnetic Resonance Imaging - NOVAâ„¢ Now Available In Europe
Wednesday, 1 October 2008   by www.medicalnewstoday.com    
Magnetic resonance flow velocity and temperature mapping of a shape memory polymer foam device
Thursday, 31 December 2009   by 7thspace.com    
MRI Resources 
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MAGNETOM Prisma
 
www.healthcare.siemens.com/magnetic-resonance-imaging/3t-mri-scanner/magnetom-prisma From Siemens Medical Systems; Received FDA clearance in 2013.
The MAGNETOM Prisma is the 3T PowerPack for exploration that offers most demanding clinical and research challenges of today and the future. The latest parallel transmit technology, TimTX TrueShape, enables zooming into specific body regions for enhanced image quality. Furthermore, the Tim 4G integrated coil technology offers remarkable imaging flexibility and supports complex examinations across the whole body.
Onsite upgrades to the MAGNETOM Prisma for customers who have already installed the 3 Tesla MAGNETOM Trio are possible.
Device Information and Specification
CLINICAL APPLICATION
Whole Body
CONFIGURATION
Ultra-short bore
3 Tesla
Head, spine, torso/ body coil, neurovascular, cardiac, neck, shoulder, knee, wrist, foot//ankle and multi-purpose flex coils. Peripheral vascular, breast, shoulder.
CHANNELS (min. / max. configuration)
64, 128
IMAGING TECHNIQUES
iPAT, mSENSE and GRAPPA (image, k-space), noncontrast angiography, radial motion compensation, Dixon
FOV
0.5 - 50 cm
BORE DIAMETER
or W x H
At isocenter: L-R 60 cm
TABLE CAPACITY
250 kg
MAGNET WEIGHT (gantry included)
13000 kg
DIMENSION H*W*D (gantry included)
173 x 230 x 222 cm
5-GAUSS FRINGE FIELD
2.6 m / 4.6 m
CRYOGEN USE
Zero boil off rate, refill approx. 10 years
COOLING SYSTEM
Water
up to 200 T/m/s
MAX. AMPLITUDE
80 mT/m
Passive, active; first order, second order
POWER REQUIREMENTS
380 / 400 / 420 / 440 / 460 / 480 V, 3-phase + ground;
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